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Lawrence J Hayward Selected Research

Hyperkalemic Periodic Paralysis

1/2020Lower Ca2+ enhances the K+-induced force depression in normal and HyperKPP mouse muscles.
12/2015Physiological basis for muscle stiffness and weakness in a knock-in M1592V mouse model of hyperkalemic periodic paralysis.
12/2015Understanding the physiology of the asymptomatic diaphragm of the M1592V hyperkalemic periodic paralysis mouse.
6/2014Contractile abnormalities of mouse muscles expressing hyperkalemic periodic paralysis mutant NaV1.4 channels do not correlate with Na+ influx or channel content.
12/2012Lessons learned from muscle fatigue: implications for treatment of patients with hyperkalemic periodic paralysis.

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Lawrence J Hayward Research Topics

Disease

24Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2019 - 05/2002
6Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019 - 06/2003
5Hyperkalemic Periodic Paralysis
01/2020 - 12/2012
2Sarcoma (Soft Tissue Sarcoma)
08/2013 - 11/2010
1Walker-Warburg Syndrome
01/2022
1Disease Progression
01/2022
1Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy)
01/2022
1Huntington Disease (Huntington's Disease)
01/2018
1Shock
10/2016
1Muscle Weakness
12/2015
1Myotonia
04/2008
1Motor Neuron Disease (Primary Lateral Sclerosis)
04/2004

Drug/Important Bio-Agent (IBA)

9Superoxide Dismutase-1IBA
01/2013 - 05/2003
8CopperIBA
11/2009 - 05/2002
8Superoxide DismutaseIBA
11/2009 - 05/2002
7Proteins (Proteins, Gene)FDA Link
01/2019 - 03/2008
7ZincIBA
11/2009 - 05/2002
3RNA-Binding Protein FUSIBA
02/2015 - 11/2010
3MetalsIBA
10/2009 - 05/2003
2arseniteIBA
01/2019 - 10/2016
2Tetrodotoxin (Tetradotoxin)IBA
12/2015 - 06/2014
2Superoxides (Superoxide)IBA
10/2009 - 05/2002
2Dyneins (Dynein)IBA
08/2008 - 06/2007
2DisulfidesIBA
06/2008 - 02/2003
1Albuterol (Salbutamol)FDA LinkGeneric
01/2020
1Adrenergic Agonists (Adrenergic Receptor Agonist)IBA
01/2020
1RNA (Ribonucleic Acid)IBA
01/2019
1OligonucleotidesIBA
01/2018
1Antisense OligonucleotidesIBA
01/2018
1Sodium-Calcium ExchangerIBA
12/2015
1Protein Isoforms (Isoforms)IBA
06/2014
1Adenosine Triphosphatases (ATPase)IBA
12/2012
1Carrier Proteins (Binding Protein)IBA
04/2011
1Nucleic AcidsIBA
04/2011
1ThyroglobulinFDA Link
04/2009
1Dynactin ComplexIBA
08/2008
1Sodium Channels (Sodium Channel)IBA
04/2008
1PotassiumIBA
04/2008
1Detergents (Detergent)IBA
03/2008
1Cysteine (L-Cysteine)FDA Link
05/2007
1Biological ProductsIBA
01/2005

Therapy/Procedure

5Therapeutics
01/2022 - 01/2005